Bills vs. Chargers odds, line: 2020 NFL picks, Week 12 predictions from proven model

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The Buffalo Bills will take on the Los Angeles Chargers at 1 p.m. ET on Sunday at Bills Stadium. The Bills are 7-3 overall and 4-1 at home, while Los Angeles is 3-7 overall and 1-4 on the road. The Bills had a three-game winning streak snapped last week. The Chargers won for the first time in four games.

Buffalo is favored by 4.5 points in the latest Bills vs. Chargers odds from William Hill Sportsbook, and the over-under is set at 52.5. Before entering any Chargers vs. Bills picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,800 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 19-10 on top-rated NFL picks this season, returning almost $800. The model also enters Week 12 on an incredible 115-75 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Bills vs. Chargers. You can head to SportsLine to see its picks. Here are several NFL betting lines for Chargers vs. Bills:

  • Bills vs. Chargers spread: Bills -4.5
  • Bills vs. Chargers over-under: 52.5 points
  • Bills vs. Chargers money line: Buffalo -220, Los Angeles 190
Latest Odds:

Bills
-4.5

What you need to know about the Bills

The Bills took a 32-30 loss against the Arizona Cardinals two weeks ago. Josh Allen threw for two TDs and 284 yards on 49 attempts in addition to picking up 38 yards on the ground and catching his first-ever TD pass. He is aiming for his third game in a row with two-plus TD passes. Allen has seven TDs (six passing) vs. 2 INTs in his past three games vs. AFC West teams. He has 15 TDs (11 passing) vs. three INTs in five home games this season,

Stefon Diggs had 10 catches for 93 yards and a TD in Week 10, his fifth game with eight-plus catches this season, tied for second in the NFL. He has 90-plus yards in his past three games. Diggs ranks second in the NFL in catches (73) and receiving yards (906) this season. Jordan Poyer leads all safeties with 80 tackles and has an interception in his past two games.

What you need to know about the Chargers

Meanwhile, Los Angeles beat the New York Jets 34-28 this past Sunday. Justin Herbert passed for three TDs and a career-high 366 yards on 49 attempts. It was his fifth game with three-plus TD passes, the most by a rookie in league history. Herbert has five games with 300-plus passing yards, tied for second most by a rookie. Herbert has two-plus TD passes in seven straight games, the longest streak by a rookie in NFL history. He leads qualified rookies in passing yards (2,699), TD passes (22) and rating (104.7).

Keenan Allen had a career-high 16 catches for 145 yards and a TD last week, becoming the fifth player in NFL history with 15-plus catches in two career games. He has 13-plus catches in six career games, the most in NFL history. He has a TD catch in the past four games. Allen leads the NFL with 81 catches. Hunter Henry has a TD catch in his past two games. The Chargers have won the past four meetings with the Bills.

How to make Chargers vs. Bills picks

The model has simulated Bills vs. Chargers 10,000 times and the results are in. It is leaning over on the total, and it’s also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Chargers vs. Bills? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to see which side of the Chargers vs. Bills spread to jump on Sunday, all from the model that enters Week 12 of the NFL season on an incredible 115-75 roll.

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